B-Lokus (Lancashire Heeler) Hunde with further clinical signs evident

with further clinical signs evident in early life

Der Test für den B-Lokus ist in drei separate Tests unterteilt

Affected dogs show signs of uncoordinated movements

Other clinical symptoms include changes in barking

Hereditary nasal parakeratosis (HNPK) is an inherited autosomal recessive skin disorder

B-Lokus (Lancashire Heeler) Hunde with further clinical signs evidentGene TYRP1 (Tyrosinase related protein 1) is responsible for chocolate liver brown colour in dogs. This coat colour is inherited recessively. There are 4 different variants on B Locus in Lancashire Heeler: bc, bs, bd and be. Combination of any two recessive alleles will result in chocolate liver brown colour (for example two bc alleles or one bc and one bs allele). Because TYRP1 gene is related to eumelanin production, it only affects dogs which have