Neuronale Zeroidlipofuszinose 12 (NCL-12) - Australian Cattle Dog Mischling Thus the dog with a

Thus the dog with a genotype b/b on B locus has all the pigmented areas changed from black to chocolate/liver brown (dog that is fawn/sable (Ay) is a livernose

Acepromazine

Dogs with two copies of mutation (homozygotes for mutation) are called „bully' Whippets

leading to progressive kidney failure

retina and other tissues

Neuronale Zeroidlipofuszinose 12 (NCL-12) - Australian Cattle Dog Mischling Thus the dog with aNeuronal ceroid lipofuscinosis is a lysosomal storage disease, characterized by neurodegeneration and decline in neurological functions at approximately 6 years of age due to accumulation of autofluorescent lysosomal storage bodies in cells of the central nervous system, as well as many other tissues. The clinical signs also include anxiety, impaired ability to recognize and respond to previously learned commands, increased sensitivity to loud or