M-Lokus (Merle inkl. Basenlänge) Aktionen verursacht durch eine Störung der

verursacht durch eine Störung der Signalübertragung an der neuromuskulären Verbindung

and respiratory failure

Krampfanfälle

This mutation was found in many dog breeds

It is characterized by abnormal hematologic findings

M-Lokus (Merle inkl. Basenlänge) Aktionen verursacht durch eine Störung derCoat pattern: The typical merle colouring is characterised by a random, patchy lightening of colour, which gives the coat a speckled appearance. Only the areas of the coat that are coloured by eumelanin (black brown pigment) are affected. Merle has a dominant effect on these areas. Coat areas coloured with the red pigment phaeomelanin are not affected by merle. A black dog with merle markings is called a blue merle, a brown dog (in the B locus b b =