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If more fat is being efficiently converted to fuel, there is less metabolic pressure to cannibalize muscle tissue

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Without adequate NAD+ levels, your mitochondria cannot produce ATP efficiently

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PIP 3 also interacts with proteins possessing a pleckstrin homology (PH) domain, such as protein kinases, including Akt and Bruton's tyrosine kinase (BTK)

Less common side effects include bladder pain, blurred vision, chest pain or discomfort, chills, confusion, coughing up blood or mucus-like material, depression, difficulty breathing or swallowing and extreme tiredness or weakness