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It has to be stressed that several features make carnitine an optimal vehicle for moving acyl groups: at first, the carnitine derivatives are more stable and less reactive with respect to the acyl-CoA (Ramsay and Arduini, 1993)
Superoxide anion is converted to peroxide by local SOD enzymes (100)
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While these concerns are valid, microdosing outside of clinical guidance is not a safe or evidence-based workaround
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