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These can vary by manufacturer

Those who progress patiently typically return stronger

Key takeaways A tirzepatide injection site reaction is usually mild, localized, and temporary, most often showing up as redness, itching, pain, or swelling where the shot was given

GFR Figure 40 Prevalence of Hypocalcemia (Adjusted for Albumin) vs

Meet our doctors Last reviewed: 04 Aug 2025 Sources Efficacy of tirzepatide 5, 10 and 15 mg versus semaglutide 2 mg in patients with type 2 diabetes: An adjusted indirect treatment comparison (2022) Diabetes Obesity & Metabolism [accessed 15 June 2025] MHRA authorises diabetes drug Mounjaro (tirzepatide) for weight management and weight loss (2023) Gov.uk [accessed 15 June 2025] Mounjaro (2023) Mounjaro [accessed 15 June 2025] Mounjaro KwikPen 2.5/5/7.5/10/12.5/15 mg solution for injection in pre-filled pen (2024) EMC [accessed 15 June 2025] Semaglutide versus dulaglutide once weekly in patients with type 2 diabetes (SUSTAIN 7): a randomised, open-label, phase 3b trial (2018) The Lancet [accessed 15 June 2025] Weight loss injections NHS weight loss injections GLP-1 for weight loss Can doctors help with weight loss

However, its important to assess how much of this perceived benefit is supported by evidence and what outcomes practitioners and patients can realistically expect