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For the kidney, degeneration of glomerular structure and dilatation of Bowmans space, degeneration of proximal and distal tubule, vascular congestion and inflammatory cell infiltration were taken into consideration

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Indeed, GLP-1 secretion is abolished upon corn oil infusion to the proximal duodenal compartment in vagotomized rats (Rocca and Brubaker, 1999)

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Fiuza-Luces C, Santos-Lozano A, Joyner M, Carrera-Bastos P, Picazo O, Zugaza JL, et al

The SELECT trial of nearly 18,000 individuals showed that 2.4mg of semaglutide reduced heart attacks, strokes, and mortality due to CVD, with 73% fewer patients progressing to diabetes compared to the control group