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That classification shapes process design, impurity profiling, and analytical control strategies

Glutathione levels decline due to increased oxidative stress, reduced synthesis capacity, mitochondrial dysfunction, chronic inflammation, and depletion of essential nutrients required for its production

Radiation Therapy Adjuvant radiation therapy is frequently recommended, especially when surgical margins are close or positive, or when tumors are large or high-grade

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Lowering the dose for a few weeks or slowing the schedule can help minimize side effects, making the medicine easier to stick with

The article states plainly that no randomized controlled trials exist comparing dual therapy to either agent alone, and that no major clinical guideline currently recommends the combination as standard therapy