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For injectable forms, long-term human safety isnt established

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Hemolysin of uropathogenic Escherichia coli evokes extensive shedding of the uroepithelium and hemorrhage in bladder tissue within the first 24 hours after intraurethral inoculation of mice

(2018) Oridonin enhances the cytotoxicity of 5-FU in renal carcinoma cells by inducting necroptotic death, Biomed

Furmaniak, J., Sanders, J., Sanders, P., Li, Y