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Females have previously been demonstrated to have substantially higher GLP-1 levels postprandially (69,70), and males have higher levels for Dipeptidyl Peptidase-4 (DPP-4), the main metabolizer of GLP-1 (71)

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Prebiotic oligosaccharides: special focus on fructooligosaccharides, its biosynthesis and bioactivity

Molecular endocrinology 28 , 860871, doi:10.1210/me.2014-1038 (2014)

This is an investigational amylin analogue titration is mandatory, starting at 0.3 mg weekly and stepping up to a 2.4 mg maintenance dose