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This is a normal physiological response to weight loss regardless of the method used to achieve it, as documented in systematic reviews of energy expenditure during weight reduction

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Lyophilized (freeze-dried) powder can be frozen for 24-36 months before reconstitution

The short answer is yes, but not because of a specific "magic number." Instead, the right age to take glutathione is tied to your bodys natural production cycle and the cumulative stress of your environment