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[PMID: 33051481] PubMed record related to this compound for laboratory literature review

Lancet Neurol 12(12):11861197 Kondoh S, Mizuno Y, Kondo T (2018) Randomized trial of istradefylline for Parkinsons disease patients with motor fluctuations

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Lyophilized peptides are peptides preserved in a dry, powdered form through freeze-drying to maintain stability during storage

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Because the milligram amount is fixed, a lighter body gets more drug exposure per pound: roughly 22% more at 70 kg and about a third less at 120 kg, compared with a 90 kg reference. The dose still comes from response and tolerability, but a lighter person is running a hotter exposure at the same number on the vial