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Pickart detailed that GHK-Cu can [5]: Reduce deep wrinkles and fine lines Tighten skin Improve skin density and elasticity Reverse the thinning of aged skin Protect skin cells from UV radiation Improve overall skin appearance Due to its properties, GHK-Cu is frequently included in cosmetic products, including anti-aging face creams [1]

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Some studies indicate that DSIP may influence endogenous opioid signaling, although its effects are not consistently reversed by opioid antagonists, suggesting indirect modulation rather than direct receptor agonism [9]

J Mol Med 95(3):323333 James R, Kesturu G, Balian G, Chhabra A (2008) Tendon: biology, biomechanics, repair, growth factors, and evolving treatment options