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Abstract Precision diabetology is increasingly becoming diabetes phenotype-driven, whereby the specific hormonal imbalances involved are taken into consideration
In a phase 1, randomized, double-blind, placebo-controlled clinical study in participants with obesity (NCT04478708), AMG 133 had an acceptable safety and tolerability profile along with pronounced dose-dependent weight loss
Weight loss tends to plateau after this period, and individual responses vary considerably
Behind the link between copper and angiogenesis: established mechanisms and an overview on the role of vascular copper transport systems
doi: 10.3389/fendo.2026.1877238 Received 10 May 2026 Revised 12 July 2026 Accepted 16 July 2026 Published 31 July 2026 Volume 17 - 2026 Edited by Yao-Wu Liu, Xuzhou Medical University, China Reviewed by Yen-Sung Huang, National Defense Medical Center, Taiwan Sara Gamal, Minia University, Egypt Updates Copyright 2026 Sun, Chen, Huang, Chen, He, Wang and Xie
However, CPAP remains a standard treatment and may still be needed in some cases
