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Dose escalation can trigger a temporary worsening that resolves within 2 to 3 weeks

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Homocysteine accumulates in the blood, causing vascular damage and micro-clotting, while downstream glutathione synthesis grinds to a halt

But a huge number of meat eaters are also deficient and likely dont know it B12 is absorbed through the stomach, and our ability to assimilate it through the stomach wall decreases with age, as well as due to any stomach issues like IBS, Crohns, and Celiac Disease, and medications that impact the stomach like metformin, antacids, PPIs, and ibuprofen

For those also living with obesity, these risks climb even higher