Through its ability to bind copper ions, GHK-Cu participates in numerous physiological processes and has become one of the most extensively studied peptides in regenerative biology, dermatological research, wound healing, connective tissue physiology, and hair follicle biology
In contrast, there was no significant decrease in the serum GSH/GSSG ratio or increase in carbonyl content of serum proteins
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It should be kept away from strong chelators (such as high levels of EDTA and related sequestrants), reducing sugars, thiol-bearing actives, and high concentrations of direct acids (for example ascorbic acid or alpha-hydroxy acids at low pH), all of which can compete for the copper center or disrupt the peptide-metal bond and shift the characteristic blue color toward brown or colorless degradation products
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