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77 studies from 17 countries were included, of which the most represented were the USA (16 studies), China (12), and Iran (6)

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[30] In December, 2020, Sinclair's group published that three Yamanaka transcription factors, Oct4, Sox2, and Klf4, when delivered together in a virus, could safely reverse the age of human and mouse cells, and restore the vision of old mice and mice with glaucoma