select trial semaglutide ppt STEP-HFpEF Trial

The area of hippocampal cells in the dentate gyrus (GD) region was increased in the STR groups compared to the CT groups

More importantly, adverse events in the semaglutide groups were mostly mild-to-moderate gastrointestinal symptoms that typically resolved within weeks as the body adapted

It controls hunger, regulates blood sugar, and slows down digestion to lower the bouts of hunger

B., Blom, H

Cagrilintide + retatrutide adds the amylin analog cagrilintide to reinforce satiety - useful when hunger is the main barrier

Additional benefits, such as modest weight loss and cardiovascular risk reduction, are considered valuable but historically secondary