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In order to ensure complete compliance with both institutional and international standards for animal research, all following operations, such as animal housing and care, dosing regimen, blood collection, and euthanasia, were carried out strictly in line with this authorized protocol

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Managing side effects during dose escalation Gastrointestinal side effects are the most commonly reported adverse events with retatrutide, and they peak during the dose escalation period

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TD Cowen analyst Steve Scala has flagged the high rate of discontinuation as a concern and suggested it could make outcomes of future trials harder to predict

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