The k red value of 1.4 10 6 M 1 s 1 for PfGrx C88S (SH) 2 is about two orders of magnitude higher than the highest k ox value for PfGrx C32S/C88S (SSG) in accordance with a physiological relevance of glutaredoxins as deglutathionylating enzymes
Incretin-based therapies for type 2 diabetes mellitus
Circulation 150(16):12881298 Neeland IJ, Linge J, Birkenfeld AL (2024) Changes in lean body mass with glucagon-like peptide-1-based therapies and mitigation strategies
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However, both medications can independently affect the gastrointestinal system , which warrants consideration