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[11] Injection site reactions are also possible

Pathogenic mutations within the prion-like domains of HNRNPA2B1 and HNRNPA1 facilitate their assembly into self-seeding fibrils and enhance their incorporation into stress granules, ultimately leading to neurodegenerative conditions such as multisystem proteinopathy and amyotrophic lateral sclerosis

While effective, the requirement for weekly injections has been a barrier for many patients

In research, it is frequently formulated into creams, serums, or hydrogels to study its effects on dermal regeneration, wound healing, and hair follicle stimulation

Significant gut microbiota compositional differences overlapping with oral health markers, like severe dental caries and sarcopenia, further underscore this systemic link (Yang et al., 2023)

Up or down-regulation of these genes provides a ground for toxicity of AFs