1.5 mg semaglutide to tirzepatide Dose-equivalence reference based on pivotal GLP-1/dual-agonist trials: SURMOUNT-1 (tirzepatide/Zepbound, 72 weeks) STEP-1 (subcutaneous semaglutide/Wegovy, 68 weeks) OASIS-4 (oral semaglutide/Wegovy, 64 weeks). For educational comparison only—these are VivioMD GLP-1 Program Overview 2026:

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Treatment burden includes weekly injections or daily tablets, frequent earlyphase contact for titration and sideeffect management, and potential insurance hurdles and outofpocket costs

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These early findings suggest GLP-1 drugs like Ozempic could even play a role in treating depression in the future