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A 2020 preclinical study evaluating gabapentin in an experimental colitis model demonstrated: Reduced visceral hypersensitivity Decreased inflammatory signaling Reduced mast cell density and activation markers in colonic tissue Downregulation of pro-inflammatory pathways (including NF-B signaling) Mast cells and enteric nerves communicate bidirectionally in the gut

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In: Chemotherapy of Infectious Diseases and Malignancies

For each sample, 1 g of total RNA was reverse-transcribed using a high-capacity cDNA reverse transcription kit (Applied Biosystems, Foster City, CA)

J Appl Crystallogr

You've likely heard of antioxidants: they are found in nutrient-dense foods like fruits and vegetables and your body makes them on its own