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Ipamorelin: The First Growth Hormone Peptide That Only Boosts GH Without Other Hormones. European journal of endocrinology.Study breakdown PubMed 2RPEP-00466Johansen, P B et al

Every dose tier outperformed placebo, but the magnitude of difference between the lowest and highest tiers reveals exactly how dose-dependent the response curve is

DMH, dorsomedial nucleus of the hypothalamus

And it means that when a stall does occur on GLP-1 therapy, the appetite component is playing a smaller role than it would on a diet, which tells you to look at other factors first

NICE guidance on eating disorders (NG69) emphasises early intervention and recommends referral to specialist eating disorder services when appropriate