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While the level of evidence for each compound varies, all of them lack the kind of large, well-controlled trials in humans that are necessary to establish safety and effectiveness, which is required for drug approvals

Progress in the Development of Biosensors Based on PeptideCopper Coordination Interaction[J]

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Pretreatment with 10 g/g GHK-Cu significantly reduced the phosphorylation of both NF-B p65 and p38 MAPK, and slightly decreased JNK1/2 phosphorylation, with no effect on ERK1/2

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