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A tirzepatida atua tambm sobre os recetores do GIP (polipeptdeo insulinotrpico dependente da glicose), combinando dois mecanismos que contribuem para o seu efeito teraputico
Retatrutide is not just a GLP-1 agonist
The key principle is that any combination therapy should be initiated and monitored under close medical supervision, with dose adjustments made based on glucose monitoring results and individual patient response
GLP-1 quadruplex receptor agonist NA-931 is the world's first agonist targeting four receptors: IGF-1 (insulin-like growth factor-1), GLP-1 (glucagon like peptide-1), GIP (glucose dependent insulinotropic polypeptide), and GCG (glucagon)
Ultimately, 1 article was included in this narrative review
2017, [2] L
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