The short half-life of native GLP-1 and advances in biochemical engineering led to the development of GLP-1 receptor agonists (GLP-1RAs)
Emerging evidence suggests that ferroptosis contributes to the pathogenesis of AP
The anticipated off-patent status of GLP-1 drugs within the next decade will furthermore allow for cheaper generic versions, making these medications more affordable and accessible
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By reducing appetite, stabilizing blood sugar, and supporting healthy eating habits, it helps patients achieve meaningful, long-term results
We propose that GLP-1 analogs are superior to DPP-4 inhibitors for managing pasireotide-induced hyperglycemia because GLP-1 analogs, unlike DPP-4 inhibitors, spare pasireotide-induced depletion of endogenous GLP-1 and restore insulin secretion suppressed by pasireotide through GLP-1R-Gs activation, counteracting the SSTRs-Gi axis
