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Unwinding of helix VI disrupts the ionic lock interactions between R348 6.37b and E408 7.63b and destabilizes the hydrogen-bond interaction between H180 2.50b and E247 3.50b
The peptide apparently also reduced the depth of wrinkles while potentially increasing skin density and thickness after 12 weeks of experimentation in skin cell models with varying degrees of photodamage
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Eur J Public Health
Reported side effects in animal models are minimal
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