M.KelberO.et al (2022)
It doesn't just work on its own
Based on reading some of the websites it seems that their hypothesis is that because ALC is involved in the Krebs cycle in the mitochondria, which gets energy from fatty acids, that means ALC helps burn fat. There is not much in the scientific literature on this topic, but I did come across an article that found no difference in metabolic parameters in study participants taking L-carnitine versus controls (not exactly the same things as acetyl-L-carnitine, but they are used somewhat similarly in the body, there just isnt the extra acetyl group in the L-carnitine)
Symptoms of over-replacement include palpitations, weight loss, tremors, insomnia, and anxiety, while under-replacement symptoms might include fatigue, weight gain, and depression
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Thats a meaningful distinction, because right now, most available medications operate within the same general family, so they have similar side effects