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Patent filings have concentrated on sequence optimization, receptor balance, and dosing regimens [5, 6], while scientific reviews increasingly position these compounds as the next frontier beyond single-target GLP-1 therapy [1, 2]

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PLoS ONE 3:e1944 Srinivasan R, Ratiney H, Hammond-Rosenbluth KE, Pelletier D, Nelson SJ (2010) MR spectroscopic imaging of glutathione in the white and gray matter at 7 T with an application to multiple sclerosis

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