reddit semaglutide results Before and after : r/Semaglutide Almost a year 32lbs :

The Lifestyle Factor Many Indians have sedentary jobs long hours at a desk, commuting, limited structured exercise

B2 -

Tirzepatide raised the bar to ~20%

This is unlikely but important to know

In addition, carnitine can also activate glucocorticoid receptor (GR) and regulate glucocorticoid- responsive genes through this mechanism, playing a role in glucocorticoid regulation [81], and reducing glucocorticoid-induced muscle atrophy in patients with pemphigus [82]

Adding semaglutide to tirzepatide would, in theory, increase total GLP-1 receptor occupancy without adding meaningful GIP activationpotentially increasing side effects without proportional clinical benefit