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5.1 GIP and GLP-1 effects on pancreas 5.1.1 Effects on pancreatic -cell insulin secretion and survival Activation of either GIPR or GLP-1R on pancreatic -cells initiates distinct yet overlapping downstream signaling cascades that ultimately amplify glucose-stimulated insulin secretion

Thus, both CI and CII exhibited a significant lower activity, which was confirmed by a lower state apparent upon Gclc ablation (Supplementary Fig

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- complete erectile function prior to the prostatectomy (this information had to be confirmed by the partner or documented in the patient's hospital file

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