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Furthermore, the KDIGO 2024 guidelines cover combination therapy from the perspective of SGLT2is being first-line therapy, and long-acting GLP-1 RAs being an add-on in adults with CKD and T2D who have not achieved individualised glycaemic targets despite use of metformin and SGLT2is, or who are unable to use those medications [2]
A, Wharton, S., Yokote, K., Zeuthen, N., & Kushner, R
Irisin improves BBB dysfunction in SAP rats by inhibiting MMP-9 via the ERK/NF-B signaling pathway
