stafford semaglutide & tirzepatide and are both injectable medications used in medical weight management—but they act on different metabolic pathways, which is why patient selection matters. Semaglutide (GLP-1 receptor agonist): • Primarily targets appetite Tirzepatide as Compared with Semaglutide

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Gastrointestinal Symptoms : GLP-1 medications already slow gastric emptyingthats part of how they work

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doi: 10.1038/s41591-022-01823-1 15 Bar-OrA.PenderM

Follow-up may depend on diabetes status, kidney disease, other medications, baseline abnormalities, dose changes, symptoms, and rate of weight loss