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Conclusions This study explored the relationship between GLP-1RAs and SSIBs through disproportionality analysis

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As dermatologists, we frequently see the physical consequences, including damaged nail plates, chronic inflammation around the nails, infections, and permanent nail changes. Now, theres still a lot we dont know about how and why GLP-1 medications work and why people experience such diverse side effects, but physicians have some theories as to why injecting yourself with semaglutide or tirzepatide might make you less likely to chomp on your fingernails

Domain I helices are shown in dark blue and beta strands are shown in red