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The JAMA study showing 30% ED resolution with an average 33-pound weight loss is one of many demonstrating this benefit

Gallstones (cholelithiasis) occurred in 4% of the semaglutide group (5 participants) and none in the placebo group

Curious about how it works, and whether it actually lives up to the hype

In the Hargreaves test, mice with CFA-induced inflammation displayed delayed recovery from heat hyperalgesia following intraplantar vehicle administration

Other side effects include nausea, vomiting and diarrhea

Tirzepatide (Zepbound) starts at 2.5mg weekly, increasing by 2.5mg every four weeks up to a maximum of 15mg, which takes approximately 20 weeks to reach if tolerated on schedule