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According to the National Institutes of Health, symptomatic magnesium deficiency due to low diet intake in healthy people is uncommon, because the kidneys limit the amount lost in urine excretion
The authors suggest this may be because most patients in their study were using GLP-1 RAs to manage diabetes rather than obesity, and because cancer treatments such as chemotherapy, steroids, and endocrine therapy can reduce the drugs weight-loss effects
Their brother, J.D
When choosing among them, factors such as glycemic efficacy, weight effects and patient preferences may take precedence over concerns about major differences in [GI] risk. She added clinicians should continue to monitor for GI symptoms, particularly early in treatment, as these events, while uncommon, remain more frequent than with some other diabetes drug classes. According to Alkabbani and colleagues, recent trials revealed that dulaglutide (Trulicity, Eli Lilly), semaglutide (Ozempic/Wegovy, Novo Nordisk) and tirzepatide (Zepbound, Eli Lilly) increased the risk for mild to serious GI adverse events like pancreatitis, constipation, nausea, vomiting and biliary disease
Most people lose 1-3kg in the first month