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The mechanism researchers find most interesting is angiogenesis, the growth of new blood vessels
Clin Cancer Res 20:28312837
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A nonexclusive alternative explanation for the kinetic patterns with HEDS (and the decreased enzyme activity at high GSH concentrations) could be a Grx(SSCH 2 CH 2 OH) intermediate that is attacked by GSH according to monothiol mechanism (i) from Fig
this page focuses on the regulatory status
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