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If you take a daily B12 supplement or multivitamin and your levels are mildly elevated (900 to 1,200 pg/mL), the most likely explanation is the supplement

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This applies to both compounds, but it is especially critical for tirzepatide where dose escalation directly impacts GI tolerability

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By providing researchers with a Certificate of Analysis (COA) that includes data generated by a named third-party laboratory, a supplier offers transparent and verifiable proof of quality

For those without malabsorption issues, oral B12 supplements may be appropriate if dietary intake is insufficient