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If you dont get enough sleep, your defense against invaders weakens

"Methylation of nicotinamide with soluble enzyme system from rat liver (in Eng)

Diagnostic and Statistical Manual of Mental Disorders

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"Effects of delta sleep-inducing peptide on free radical processes under stress." Bulletin of Experimental Biology and Medicine

It does so by also potentiating FSH actions on granulosa cells, and it was demonstrated that the IGFR was absolutely required for FSH-mediated activation of the PI3K/Akt pathway which is a pro-survival cascade, and subsequent granulosa cell differentiation (59, 60)