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A B12 shot is a quick intramuscular injection of vitamin B12 (cobalamin) that bypasses the stomach acid, liver metabolism, and intestinal absorption issues that limit oral B12 to roughly 1% bioavailability in most adults

Though anecdotal, these findings mirror animal data

Fu, Q., Zhang, J., Sa, Y-L., Jin, S-B

Thiamine plays a crucial role in carbohydrate metabolism, nerve signal transmission, and energy production at the cellular level

B12 also promotes healthy brain and nerve function, aids in fat metabolism, and helps prevent anemia-related exhaustion

409,410 Repurposing Pentoxifylline Pentoxifylline (Pentopak, Pentoxil, or Trental) is a drug that reduces blood viscosity and improves blood flow