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However, not all triple GLP-1/GIP/GCG agonists are advancing to late-stage clinical trials
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[Abstract] EMBO J
The 2006 Ionescu paper documented that pulsatile GH secretion persists even under continuous receptor stimulation, suggesting somatotroph-intrinsic pulsatile release dynamics independent of receptor-binding temporal patterns (PMID 17018654)
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