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PregS may affect CICR indirectly by activation of NMDARs or L-type voltage-gated Ca 2+ channels (L-Type VGCCs) and not by direct activation of the Ca 2+ release-activated Ca 2+ channel protein 1 (ORAI1) or stromal interaction molecule 1 (STIM1)

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Natural killer (NK) cells, although part of innate immunity, are also implicated

This ratio was vehicle-corrected by subtracting the response of vehicle-treated wells from the ratio of ligand-treated wells and then baseline-corrected by subtracting to the mean BRET ratio of baseline values (prestimulation) for each well

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