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However, the results of preliminary studies seem promising ( For example, a small study in children with bipolar spectrum disorders showed reduced symptoms of mania and depression when a combination of 3 grams of omega-3 fatty acids and up to 2 grams of inositol were taken daily for 12 weeks ( In addition, studies suggest that 36 grams of inositol taken daily may help reduce symptoms of psoriasis caused by lithium, a common medication used to treat bipolar disorder ( Summary Though more research is needed, inositol shows potential as an alternative treatment option for mental health conditions, including panic disorder, depression and bipolar disorder

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Abnormalities in selenium metabolism and skeletal development diseases Selenium deficiency is regarded as one of the initiating factors of KBD, which is an endemic osteoarthropathy caused by the premature closure of epiphyseal plate and the impaired skeletal development