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Protein disulfide isomerase A3 regulates influenza neuraminidase activity and influenza burden in the lung

| Trilinolein (Natural Product) | NF-B pathway, MAPK pathway (JNK, ERK, p38), AMPK-mTOR pathway [1] [2] [3] | Suppresses iNOS, COX-2, TNF-, IL-1, IL-6

BCAA catabolism-targeted therapy improved HFpEF phenotypes (59), and GRSF1 protected against heart failure by maintaining BCAA homeostasis (60)

The WHO estimates that more than 1 billion people worldwide are living with obesity, a condition that significantly increases the risk of cardiovascular disease, type 2 diabetes, cancer, and premature mortality

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