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AICART: aminoimidazolecarboxamide ribonucleotide transferase BHMT: betaine-homocysteine methyltransferase CBS: cystathionine -synthase CTGL: -cystathionase DHFR: dihydrofolate reductase DMGD: dimethylglycine dehydrogenase DNMT: DNA-methyltransferase FTD: 10-formyltetrahydrofolate dehydrogenase FTS: 10-formyltetrahydrofolate synthase GCS: -glutamylcysteine synthetase GDC: glycine decarboxylase (glycine cleavage system) GNMT: glycine N-methyltransferase GPX: glutathione peroxidase GR: glutathione reductase GS: glutathione synthetase MAT-I: methionine adenosyl transferase I MAT-III: methionine adenosyl transferase III MS: methionine synthase MTCH: 5,10-methenyltetrahydrofolate cyclohydrolase MTD: 5,10-methylenetetrahydrofolate dehydrogenase MTHFR: 5,10-methylenetetrahydrofolate reductase NE: non-enzymatic conversion PGT: Phosphoribosyl glycinamidetransformalase SAAH: S-adenosylhomocysteine hydrolase SDH: sarcosine dehydrogenase SHMT: serinehydroxymethyltransferase TS: thymidylate synthase Metabolites
RSC Adv 5(128):106171106181
Administration Precautions: Bacteriostatic Water for Injection should never be injected intravenously (or intra-spinally) by itself without first being mixed with a medication or appropriate solute
As mentioned above, the human GSTP1-1 may form an oxidized enzyme involving the two more reactive cysteines (i.e., Cys47 and Cys101)
Glutathione is not recommended for individuals with asthma, or those who are pregnant or breastfeeding
Cozmin M, Lungu II, Gutu C, Stefanache A, Duceac LD, oltuzu BD, et al
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