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Accumulating evidence suggests that gut microbiota dysbiosis is involved in IBS pathophysiology, with IBS-associated dysbiosis generally characterized by reduced microbial diversity, depletion of protective commensals, and enrichment of symptom-associated taxa [260]
Martens MD et al
People living with these autoimmune diseases are at a higher risk of heart problems due to the chronic inflammation associated with these diseases
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HMGB1 can transmit signals during inflammation, leading to the synthesis and release of proinflammatory factors
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