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For example, B12 shots are generally inappropriate for people who have: Allergies to cobalamin, cobalt, or any of the ingredients in B12 injections Taking B12 shots with any of these allergies could lead to a seriouspotentially life-threateningallergic reaction

However, that will only happen if fatigue is caused by being B12 deficient before the shots are started

This comprehensive laboratory surveillance helps rule out organ toxicity or bone marrow suppression that might occur with extended exposure

Lebers disease B12 injections could cause permanent optic nerve damage and even blindness in someone with this inherited eye disorder

In conclusion, this study demonstrated that intra-articular injections of AOD9604 improved cartilage health and functional recovery in a rabbit OA model

They are research context, not proven human dosing