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GLP-1 RAs are contraindicated during pregnancy due to limited safety data and potential embryofetal risk
Injectable GLP-1 medications can be given at any time, but oral semaglutide (Rybelsus) also requires fasting administration, so consider bedtime levothyroxine dosing with careful TSH monitoring
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Hormonal effects: In women, insulin resistance drives elevated androgens, contributing to PCOS and its symptoms
How to stay hydrated on semaglutide or tirzepatide A few habits that work well for our patients: Sip on a schedule
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