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Negative control and Nrf2 siRNA used in this study were manufactured by Hanbio (Shanghai, China)
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Dysregulation of autophagy, endolysosomal trafficking, lysosomal function, and mitochondrial integrity not only promotes neuronal dysfunction and death but also contributes to protein aggregation, neuroinflammation, and disease propagation across neural networks
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Considered one the worlds healthiest diets, the Mediterranean Diet is rich in polyunsaturated (namely omega-3) and monounsaturated fats, high quality protein, complex carbohydrates and fibre, as well as being abundant in essential vitamins, minerals and phytonutrients that together contribute to its potent ability to reduce oxidative stress and inflammation
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